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ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR
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DeCS
Descriptor
English
:
Advanced Glycosylation End Product-Specific Receptor
Descriptor
Spanish
:
Receptor Específico para Productos Finales de Glicosilación Avanzada
Descriptor
Portuguese
:
Receptor Específico para Produtos Finais de Glicosilação Avançada
Tree Number:
D12.776.543.750.006
Definition
English
:
A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED
GLYCOSYLATION
END PRODUCTS to mediate cellular responses to both acute and chronic vascular
inflammation
in conditions such as
ATHEROSCLEROSIS
and
DIABETES MELLITUS
, TYPE 2 . It also binds
AMYLOID
BETA
PEPTIDES
and the
alarmins
S100A12 and
S100 CALCIUM BINDING PROTEIN BETA SUBUNIT
.
History Note
English
:
2016 (1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
55997
Unique Identifier:
D000067759
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS